Ondansetron
Ondansetron (Zofran) is used to prevent nausea and vomiting during cancer treatment or after surgery. This catalogue includes one Zofran tablet formulation for this ingredient.
Medicine containing Ondansetron
Key points
- 5-HT3 receptor antagonist: Ondansetron blocks a signal involved in nausea and vomiting.
- Heart rhythm warning: Avoid ondansetron if you have congenital long QT syndrome.
- ECG monitoring: The label directs monitoring with an ECG where there are electrolyte abnormalities, cardiac failure, arrhythmias, or other QT-prolonging medicines.
Common questions about ondansetron
Can ondansetron be taken with apomorphine?
No. Ondansetron and apomorphine must not be used together. The product information lists this combination as a contraindication, meaning the two medicines should not be taken at the same time.
What is known about ondansetron and serotonergic medicines?
Serotonin syndrome has been reported with 5-HT3 receptor antagonists, particularly when they are used with serotonergic medicines. The product information gives this warning for ondansetron, including the Zofran tablet listed here.
